Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p063 | (1) | WCRB2014

Roles of the untranslated regions in the translational regulation of cyclin A2 in murine oocytes and embryos

Mori Yuuka , Aoki Fugaku

After the resumption of meiosis and fertilization, differentiated oocytes dramatically change their nature to generate totipotent zygotes. However, since transcription does not occur in oocytes and early 1-cell stage embryos, gene expression is controlled only by post-transcriptional regulation. There are huge mRNAs stored in full-grown oocytes (FGO). A part of them is not translated in FGO and MII stage oocytes, and become translated after the resumption of meiosis and fertil...